Inula viscosa studies by Avisco Ltd.

    Clinical studies

    Anti-oxidant activity of Avisco’s Inula viscosa extract
    Summary of anti-oxidant activity study carried out in comparison to  benchmark anti-oxidants BHT (synthetic)  and quercetin
    (a natural anti-oxidant found in green tea and other herbs)
    The results show Inula viscosa extracts delay of β-Carotene degradation caused by oxidation equal or better than benchmark anti-
    oxidants.




























    Anti inflammatory activity of Inula viscosa extract
    Aivorex™ is the trade name for Avisco’s extract derived from the leaves of Inula viscosa.
    In order to verify the biological activity of Aivorex™  as an anti-inflammatory agent, a study was conducted
    using the mouse ear edema assay. Verification of the anti-inflammatory properties of Inula viscosa extract was
    provided  from clinical trials on Osteo-arthritis, clearly an inflammatory condition

















    The effect of of Aivorex™ topical application at various concentrations in preventing inflammation was measured.
    The data shows that with a concentration as low as 2%, Aivorex™  is sufficient  in reducing inflammation by as much as 60%.

    Preservation performance
    High efficacy anti-fungal, anti-bacterial and anti-yeast activity
    Through Avisco’s proprietary studies,  Aivorex™ Avisco's Inula viscosa extract demonstrated high efficacy as growth inhibitor
    of a broad spectrum of fungi, bacteria, molds, mildews and yeasts at very low concentrations.




















    Mode of action Vs decay causing fungi - please inquire

    Chemical constituency and chemical markers
    Each batch of Inula viscosa extract produced by Avisco for use in its formulations is analyzed  to determine that its chemical
    markers are within standardization range.
    Leading chemical markers of Avisco Inula oleoresin extract include 35% tomentosin and sesquiterpenic lactones,
    13.5 % bioflavanoids, 0.5% carotanoids, sterols, saponins and fatty acids









            



























    Routine Chromatography analysis are conducted for quality control
    and standardization of  Avisco’s Inula viscosa extract


















































     Copyright © 2002-2008 Avisco Ltd.    All rights reserved
    The information presented in this page is proprietary, it may not be
     reproduced or distributed without the explicit written consent of Avisco Ltd.
       Other Inula viscosa related proprietary studies by Avisco Ltd:

  1. Biological activity and yield screening studies of various wild Inula viscosa phenotypes
  2. Cultivation as a standardized crop study of various Inula viscosa phenotypes
  3. Harvest technology and post harvest processing studies
  4. Inula viscosa extraction methods Vs extract biological activity screening studies
  5. Development and optimization of industrial extraction methods
  6. Chemical composition and chemical markers studies for extract standardization
  7. Biological activity studies of Fungi, Bacteria, Mold, and Mildew growth inhibition
  8. Inula viscosa extract growth inhibition of marine fouling organisms
  9. Clinical studies as treatment for Osteoarthritis
  10. Clinical study as a treatment for Athlete foot
  11. Preservation performance studies for food, and cosmetics
  12. Wood preservation with Inula viscosa extract study
  13. Formulations of waterborne and oil borne Inula viscosa extract preparations
  14. Toxicity studies
  15. Anti inflammatory activity studies
Avisco Ltd. World leader in Inula viscosa research, production, applications and products
      AIVOREX
      (Avisco's Inula Viscosa Oleo Resin Extract)

     Toxicity Study results


    Acute Oral Toxicity              LD50     > 2000 mg/kg  rat
    Method     OECD 423
     Not representing an acute toxic risk


    Acute Dermal Toxicity         Primary irritation index 1.1 rabbit    Method   OECD 404
    Not representing an acute toxic risk


    Acute Eye Irritation                 LD50             >2000 mg/kg rabbit
    Method           OECD 402
    May be categorized as non irritant to the eye